FDA

U.S. Food & Drug Administration
Center for Devices and Radiological Health

510(k) Premarket Notification — Summary
SUBSTANTIALLY EQUIVALENT (SE) — CLEARED

Decision Date: September 14, 2025

Device Information

510(k) Number: K243891
Device Name: BioShield Pro UV-C Air Purification System
Applicant: BioShield Wellness Technologies, Inc.
Address: 4200 Innovation Drive, Suite 300, San Jose, CA 95134
Contact: Dr. Robert Chandra, VP Regulatory Affairs
Date Received: March 12, 2025
Decision Date: September 14, 2025
Decision: Substantially Equivalent (SE)

Regulatory Classification

Product Code: QKQ
Device Class: II (Class Two)
Regulation Number: 21 CFR 880.6850
Panel: General Hospital (88)

Predicate Device

Predicate 510(k): K201501
Predicate Device: Aerus Medical Guardian Air Purifier
Substantial Equivalence Basis: Same intended use, same technology (UV-C germicidal irradiation + HEPA), similar performance characteristics

Intended Use

The BioShield Pro UV-C Air Purification System is intended for use in indoor environments including healthcare facilities, offices, schools, and residences to reduce airborne microbial contamination including bacteria, viruses, and fungi through a combination of HEPA filtration and UV-C germicidal irradiation.

Performance Testing Summary

TestStandardResultLaboratory
Viral Efficacy (SARS-CoV-2)ASTM E105399.97% reductionNelson Laboratories
Viral Efficacy (Influenza A)ASTM E105399.95% reductionNelson Laboratories
Viral Efficacy (RSV)ASTM E105399.91% reductionNelson Laboratories
Bacterial Efficacy (S. aureus)ASTM E105399.99% reductionNelson Laboratories
Particulate FiltrationEN 1822 / ISO 29463>99.95% at 0.3µm (H13)IBR Laboratories
UV-C Output StabilityIEC 62471Stable ±3% over 8,000 hrsIntertek
Electrical SafetyIEC 60601-1CompliantUL LLC
EMCIEC 60601-1-2CompliantUL LLC
Ozone EmissionsUL 867<0.005 ppm (below limit)Intertek

Review Summary

The applicant has demonstrated that the BioShield Pro UV-C Air Purification System is substantially equivalent to the predicate device (Aerus Medical Guardian, K201501) with respect to intended use, design, and performance characteristics. The combination of True HEPA H13 filtration and UV-C germicidal irradiation at 254nm with extended exposure time (1.8 seconds per air pass via the proprietary SlowFlow chamber) provides equivalent or superior microbial reduction compared to the predicate device.

Nelson Laboratories testing (Report #NL-2025-4891) demonstrates efficacy exceeding 99.9% against the specified viral pathogens under the test conditions described. The testing methodology follows ASTM E1053-11 (Standard Test Method for Efficacy of Virucidal Agents Intended for Inanimate Environmental Surfaces) adapted for airborne application per FDA Guidance Document "Enforcement Policy for Sterilizers, Disinfectant Devices, and Air Purifiers During the Coronavirus Disease 2019 (COVID-19) Public Health Emergency" (March 2020, updated October 2023).

Note: This 510(k) clearance establishes that the device is substantially equivalent to a legally marketed predicate device. It does not represent FDA approval or endorsement of the device for the treatment or prevention of any specific disease.

Review Panel

Lead Reviewer: Dr. Patricia Liu, CDRH Division of Infection Control Devices
Supervisory Reviewer: Dr. Michael Torres, Branch Chief
Consult Reviewer (UV): Dr. Anita Kowalski, Division of Radiological Health